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Sequence Detail
P15533 Q3UZ29 Q99K55 Q99PQ7 Q99PQ9 Q3UV85 Q99PQ8 (UniProt | EBI) Last sequence update: 2002-02-11
Last annotation update: 2019-12-11
from provider
RecName: Full=Tripartite motif-containing protein 30A;AltName: Full=Down regulatory protein of interleukin-2 receptor;AltName: Full=Tripartite motif-containing protein 30;
Polypeptide 496 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Trim30a tripartite motif-containing 30A 18 4 1 4
Sequence references in MGI J:9134 Patarca R, et al., rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1 [published erratum appears in Proc Natl Acad Sci U S A 1988 Jul;85(14):5224. Proc Natl Acad Sci U S A. 1988 Apr;85(8):2733-7
J:69273 Reymond A, et al., The tripartite motif family identifies cell compartments. EMBO J. 2001 May 1;20(9):2140-51
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:133259 Shi M, et al., TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation. Nat Immunol. 2008 Apr;9(4):369-77
J:162981 Tareen SU, et al., An expanded clade of rodent Trim5 genes. Virology. 2009 Mar 15;385(2):473-83
J:167485 Hu Y, et al., Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production. J Immunol. 2010 Dec 15;185(12):7699-705

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory