Sequence Detail

ID/Version

P15379 Q05732 Q62061 Q62409 Q62060 Q62063 Q61395 Q99J14 Q9QYX8 Q64296 Q62062 Q62408 (UniProt | EBI)

Last sequence update: 2003-04-30
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=CD44 antigen;AltName: Full=Extracellular matrix receptor III; Short=ECMR-III;AltName: Full=GP90 lymphocyte homing/adhesion receptor;AltName: Full=HUTCH-I;AltName: Full=Hermes antigen;AltName: Full=Hyaluronate receptor;AltName: Full=L

Provider

SWISS-PROT

Sequence

Polypeptide 778 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd44	CD44 antigen	99	170	4	29

Sequence references in MGI

J:4284 Tolg C, et al., Splicing choice from ten variant exons establishes CD44 variability. Nucleic Acids Res. 1993 Mar 11;21(5):1225-9
J:10086 Zhou DF, et al., Molecular cloning and expression of Pgp-1. The mouse homolog of the human H-CAM (Hermes) lymphocyte homing receptor. J Immunol. 1989 Nov 15;143(10):3390-5
J:10093 Nottenburg C, et al., Isolation of mouse CD44 cDNA: structural features are distinct from the primate cDNA. Proc Natl Acad Sci U S A. 1989 Nov;86(21):8521-5
J:10168 Wolffe EJ, et al., The cDNA sequence of mouse Pgp-1 and homology to human CD44 cell surface antigen and proteoglycan core/link proteins. J Biol Chem. 1990 Jan 5;265(1):341-7
J:12600 Screaton GR, et al., The identification of a new alternative exon with highly restricted tissue expression in transcripts encoding the mouse Pgp-1 (CD44) homing receptor. Comparison of all 10 variable exons between mouse, human, and rat. J Biol Chem. 1993 Jun 15;268(17):12235-8
J:34882 Yu Q, et al., A new alternatively spliced exon between v9 and v10 provides a molecular basis for synthesis of soluble CD44. J Biol Chem. 1996 Aug 23;271(34):20603-7
J:41342 He Q, et al., Molecular isoforms of murine CD44 and evidence that the membrane proximal domain is not critical for hyaluronate recognition. J Cell Biol. 1992 Dec;119(6):1711-9
J:62867 Wittig BM, et al., Abrogation of experimental colitis correlates with increased apoptosis in mice deficient for CD44 variant exon 7 (CD44v7). J Exp Med. 2000 Jun 19;191(12):2053-64
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:156410 Terawaki S, et al., The PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding module. EMBO J. 2010 Jan 6;29(1):236-50
J:184685 Wilson CH, et al., Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation. EMBO J. 2012;31(11):2486-97
J:224716 Wu C, et al., Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells. Immunity. 2014 Aug 21;41(2):270-82
J:255604 Yonemura S, et al., Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2. J Cell Biol. 1998 Feb 23;140(4):885-95
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89