Sequence Detail

ID/Version

P12961 Q8CCZ3 Q9D2P6 Q9CYP0 Q9DB14 (UniProt | EBI)

Last sequence update: 1990-01-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Neuroendocrine protein 7B2;AltName: Full=Secretogranin V;AltName: Full=Secretogranin-5;AltName: Full=Secretory granule endocrine protein I;Contains: RecName: Full=N-terminal peptide;Contains: RecName: Full=C-terminal peptide;Flags: Precurs

Provider

SWISS-PROT

Sequence

Polypeptide 212 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Scg5	secretogranin V	12	109	3	7

Sequence references in MGI

J:22953 Mbikay M, et al., cDNA sequence of neuroendocrine protein 7B2 expressed in beta cell tumors of transgenic mice. Int J Pept Protein Res. 1989 Jan;33(1):39-45
J:53349 Westphal CH, et al., The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease. Cell. 1999 Mar 5;96(5):689-700
J:70579 Mbikay M, et al., Neuroendocrine secretory protein 7B2: structure, expression and functions. Biochem J. 2001 Jul 15;357(Pt 2):329-42
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113664 Muller L, et al., Mechanism of the facilitation of PC2 maturation by 7B2: involvement in ProPC2 transport and activation but not folding. J Cell Biol. 1997 Nov 3;139(3):625-38
J:113691 Martens GJ, et al., The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):5784-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89