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Sequence Detail
P11835 Q64482 (UniProt | EBI) Last sequence update: 1998-07-15
Last annotation update: 2020-02-26
from provider
RecName: Full=Integrin beta-2;AltName: Full=Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta;AltName: Full=Complement receptor C3 subunit beta;AltName: CD_antigen=CD18;Flags: Precursor;
Polypeptide 771 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Itgb2 integrin beta 2 71 84 8 15
Sequence references in MGI J:9930 Wilson RW, et al., Nucleotide sequence of the cDNA from the mouse leukocyte adhesion protein CD18. Nucleic Acids Res. 1989 Jul 11;17(13):5397
J:137848 Xu J, et al., Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating beta2 integrins. Nat Immunol. 2008 Aug;9(8):880-6
J:155307 Baruzzi A, et al., c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration. FEBS Lett. 2010 Jan 4;584(1):15-21

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory