Sequence Detail

ID/Version

P11477 Q61448 (UniProt | EBI)

Last sequence update: 1990-08-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Alpha-defensin 1;AltName: Full=Cryptdin-1;AltName: Full=Defensin-related cryptdin peptide;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 93 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Defa1	defensin, alpha 1	31	3	6	0

Sequence references in MGI

J:1458 Ouellette AJ, et al., Purification and primary structure of murine cryptdin-1, a Paneth cell defensin. FEBS Lett. 1992 Jun 15;304(2-3):146-8
J:10551 Ouellette AJ, et al., A novel mouse gene family coding for cationic, cysteine-rich peptides. Regulation in small intestine and cells of myeloid origin [published erratum appears in J Biol Chem 1994 Jul 15;269(28):18702]. J Biol Chem. 1990 Jun 15;265(17):9831-7
J:16918 Huttner KM, et al., Structure and diversity of the murine cryptdin gene family. Genomics. 1994 Feb;19(3):448-53
J:17286 Selsted ME, et al., Enteric defensins: antibiotic peptide components of intestinal host defense. J Cell Biol. 1992 Aug;118(4):929-36
J:19933 Ouellette AJ, et al., Developmental regulation of cryptdin, a corticostatin/defensin precursor mRNA in mouse small intestinal crypt epithelium. J Cell Biol. 1989 May;108(5):1687-95