Sequence Detail

ID/Version

P11276 G5E8B8 Q64233 Q80UI4 Q61568 Q61567 Q61569 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Fibronectin {ECO:0000305}; Short=FN;Contains: RecName: Full=Anastellin;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 2477 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fn1	fibronectin 1	104	251	4	73

Sequence references in MGI

J:2797 Khandjian EW, et al., Fibronectin gene expression in proliferating, quiescent, and SV40-infected mouse kidney cells. Exp Cell Res. 1992 Oct;202(2):464-70
J:16652 Polly P, et al., Sequence of the mouse fibronectin-encoding gene promoter region. Gene. 1993 Dec 31;137(2):353-4
J:21812 Blatti SP, et al., Induction of fibronectin gene transcription and mRNA is a primary response to growth-factor stimulation of AKR-2B cells. Proc Natl Acad Sci U S A. 1988 Feb;85(4):1119-23
J:26253 Talts JF, et al., Regulation of mesenchymal extracellular matrix protein synthesis by transforming growth factor-beta and glucocorticoids in tumor stroma. J Cell Sci. 1995 Jun;108(Pt 6):2153-62
J:126743 de Vega S, et al., TM14 is a new member of the fibulin family (fibulin-7) that interacts with extracellular matrix molecules and is active for cell binding. J Biol Chem. 2007 Oct 19;282(42):30878-88
J:175678 Brunner M, et al., Osteoblast mineralization requires beta1 integrin/ICAP-1-dependent fibronectin deposition. J Cell Biol. 2011 Jul 25;194(2):307-22
J:239189 Kraft-Sheleg O, et al., Localized LoxL3-Dependent Fibronectin Oxidation Regulates Myofiber Stretch and Integrin-Mediated Adhesion. Dev Cell. 2016 Mar 07;36(5):550-61
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:314650 Su MT, et al., Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice. Int Immunol. 2021 Jul 23;33(8):447-458
J:333810 Elenbaas JS, et al., SVEP1 is an endogenous ligand for the orphan receptor PEAR1. Nat Commun. 2023 Feb 15;14(1):850
J:334841 Kuramoto K, et al., Exercise-activated hepatic autophagy via the FN1-alpha5beta1 integrin pathway drives metabolic benefits of exercise. Cell Metab. 2023 Feb 14;