Sequence Detail

ID/Version

P10923 Q91VH4 P19008 (UniProt | EBI)

Last sequence update: 1989-07-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Osteopontin;AltName: Full=2AR;AltName: Full=Bone sialoprotein 1;AltName: Full=Calcium oxalate crystal growth inhibitor protein;AltName: Full=Early T-lymphocyte activation 1 protein;AltName: Full=Minopontin;AltName: Full=Secreted phosphoprote

Provider

SWISS-PROT

Sequence

Polypeptide 294 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Spp1	secreted phosphoprotein 1	54	201	2	52

Sequence references in MGI

J:9812 Miyazaki Y, et al., Nucleotide sequence of cDNA for mouse osteopontin-like protein. Nucleic Acids Res. 1989 Apr 25;17(8):3298
J:9889 Patarca R, et al., Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection. J Exp Med. 1989 Jul 1;170(1):145-61
J:10690 Miyazaki Y, et al., The mouse osteopontin gene. Expression in monocytic lineages and complete nucleotide sequence. J Biol Chem. 1990 Aug 25;265(24):14432-8
J:22333 Craig AM, et al., Osteopontin, a transformation-associated cell adhesion phosphoprotein, is induced by 12-O-tetradecanoylphorbol 13-acetate in mouse epidermis. J Biol Chem. 1989 Jun 5;264(16):9682-9
J:60284 Ashkar S, et al., Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science. 2000 Feb 4;287(5454):860-4
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:233254 Narisawa S, et al., In vivo overexpression of tissue-nonspecific alkaline phosphatase increases skeletal mineralization and affects the phosphorylation status of osteopontin. J Bone Miner Res. 2013 Jul;28(7):1587-98
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:315946 Sato-Nishiuchi R, et al., Polydom/SVEP1 is a ligand for integrin alpha9beta1. J Biol Chem. 2012 Jul 20;287(30):25615-30