Sequence Detail

ID/Version

P10852 G3UWA6 Q54AH5 (UniProt | EBI)

Last sequence update: 1989-07-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Amino acid transporter heavy chain SLC3A2 {ECO:0000305};AltName: Full=4F2 cell-surface antigen heavy chain {ECO:0000303|PubMed:2928113}; Short=4F2hc {ECO:0000250|UniProtKB:P08195};AltName: Full=Solute carrier family 3 member 2 {ECO:0

Provider

SWISS-PROT

Sequence

Polypeptide 526 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc3a2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	77	111	5	94

Sequence references in MGI

J:16840 Parmacek MS, et al., Structure, expression and regulation of the murine 4F2 heavy chain. Nucleic Acids Res. 1989 Mar 11;17(5):1915-31
J:52426 Nakamura E, et al., 4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer. J Biol Chem. 1999 Jan 29;274(5):3009-16
J:61338 Fukasawa Y, et al., Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids. J Biol Chem. 2000 Mar 31;275(13):9690-8
J:93968 Tsumura H, et al., The targeted disruption of the CD98 gene results in embryonic lethality. Biochem Biophys Res Commun. 2003 Sep 5;308(4):847-51
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89