Sequence Detail

ID/Version

P10749 Q2M4J6 (UniProt | EBI)

Last sequence update: 1989-07-01
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Interleukin-1 beta; Short=IL-1 beta;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 269 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Il1b	interleukin 1 beta	183	122	3	22

Sequence references in MGI

J:8581 Telford JL, et al., The murine interleukin 1 beta gene: structure and evolution. Nucleic Acids Res. 1986 Dec 22;14(24):9955-63
J:20076 Gray PW, et al., Two interleukin 1 genes in the mouse: cloning and expression of the cDNA for murine interleukin 1 beta. J Immunol. 1986 Dec 1;137(11):3644-8
J:106976 Mariathasan S, et al., Cryopyrin activates the inflammasome in response to toxins and ATP. Nature. 2006 Mar 9;440(7081):228-32
J:120763 Brough D, et al., Caspase-1-dependent processing of pro-interleukin-1beta is cytosolic and precedes cell death. J Cell Sci. 2007 Mar 1;120(Pt 5):772-81
J:149937 Qu Y, et al., Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J Immunol. 2007 Aug 1;179(3):1913-25