Sequence Detail

ID/Version

P10637 Q91WK4 A2A5Y9 Q60684 Q60685 P10638 Q60686 Q62286 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Microtubule-associated protein tau {ECO:0000305};AltName: Full=Neurofibrillary tangle protein;AltName: Full=Paired helical filament-tau; Short=PHF-tau;

Provider

SWISS-PROT

Sequence

Polypeptide 733 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mapt	microtubule-associated protein tau	146	133	4	297

Sequence references in MGI

J:1166 Couchie D, et al., Primary structure of high molecular weight tau present in the peripheral nervous system. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4378-81
J:21223 Sawa A, et al., Molecular diversity at the carboxyl terminus of human and rat tau. Brain Res Mol Brain Res. 1994 Nov;27(1):111-7
J:27179 Lee G, et al., The primary structure and heterogeneity of tau protein from mouse brain. Science. 1988 Jan 15;239(4837):285-8
J:96030 Kishi M, et al., Mammalian SAD kinases are required for neuronal polarization. Science. 2005 Feb 11;307(5711):929-32
J:162066 Barnes AP, et al., LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell. 2007 May 4;129(3):549-63
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93
J:224517 Morris M, et al., Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice. Nat Neurosci. 2015 Aug;18(8):1183-9
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89