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Sequence Detail
ID/Version
P10148 Q9QYD7 (UniProt | EBI) Last sequence update: 1989-07-01
Last annotation update: 2021-02-10
Sequence
description
from provider
RecName: Full=C-C motif chemokine 2;AltName: Full=Monocyte chemoattractant protein 1;AltName: Full=Monocyte chemotactic protein 1; Short=MCP-1;AltName: Full=Platelet-derived growth factor-inducible protein JE;AltName: Full=Small-inducible cytokine
Provider SWISS-PROT
Sequence
Polypeptide 148 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ccl2 chemokine (C-C motif) ligand 2 90 73 4 14
Sequence references in MGI J:17920 Van Damme J, et al., Production and identification of natural monocyte chemotactic protein from virally infected murine fibroblasts. Relationship with the product of the mouse competence (JE) gene. Eur J Biochem. 1991 Jul 1;199(1):223-9
J:17998 Rollins BJ, et al., Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc Natl Acad Sci U S A. 1988 Jun;85(11):3738-42
J:39114 Kawahara RS, et al., Platelet-derived growth factor-inducible gene JE is a member of a family of small inducible genes related to platelet factor 4. J Biol Chem. 1989 Jan 15;264(2):679-82
J:56752 Teuscher C, et al., Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis. J Immunol. 1999 Aug 15;163(4):2262-6
J:194299 Ueno M, et al., Fat-specific protein 27 modulates nuclear factor of activated T cells 5 and the cellular response to stress. J Lipid Res. 2013 Mar;54(3):734-43
J:269680 Wu XB, et al., Chemokine receptor CCR2 contributes to neuropathic pain and the associated depression via increasing NR2B-mediated currents in both D1 and D2 dopamine receptor-containing medium spiny neurons in the nucleus accumbens shell. Neuropsychopharmacology. 2018 Oct;43(11):2320-2330

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory