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Sequence Detail
ID/Version
P10107 (UniProt | EBI) Last sequence update: 2007-01-23
Last annotation update: 2019-07-03
Sequence
description
from provider
RecName: Full=Annexin A1;AltName: Full=Annexin I;AltName: Full=Annexin-1;AltName: Full=Calpactin II;AltName: Full=Calpactin-2;AltName: Full=Chromobindin-9;AltName: Full=Lipocortin I {ECO:0000303|PubMed:2974946};AltName: Full=Phospholipase A2 inhibitory pr
Provider SWISS-PROT
Sequence
Polypeptide 346 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Anxa1 annexin A1 145 9 9 3
Sequence references in MGI J:9543 Sakata T, et al., Mouse lipocortin I cDNA. Nucleic Acids Res. 1988 Dec 23;16(24):11818
J:11326 Horlick KR, et al., Mouse lipocortin I gene structure and chromosomal assignment: gene duplication and the origins of a gene family. Genomics. 1991 Jun;10(2):365-74
J:81498 Hannon R, et al., Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB J. 2003 Feb;17(2):253-5
J:87169 Lennon NJ, et al., Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing. J Biol Chem. 2003 Dec 12;278(50):50466-73
J:125876 Reynolds SD, et al., CCSP regulates cross talk between secretory cells and both ciliated cells and macrophages of the conducting airway. Am J Physiol Lung Cell Mol Physiol. 2007 Jul;293(1):L114-23
J:126333 D'Acquisto F, et al., Impaired T cell activation and increased Th2 lineage commitment in Annexin-1-deficient T cells. Eur J Immunol. 2007 Nov;37(11):3131-42
J:142735 Babbin BA, et al., Annexin A1 regulates intestinal mucosal injury, inflammation, and repair. J Immunol. 2008 Oct 1;181(7):5035-44
J:182881 Patel DM, et al., Annexin A1 is a new functional linker between actin filaments and phagosomes during phagocytosis. J Cell Sci. 2011 Feb 15;124(Pt 4):578-88
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:220546 Leoni G, et al., Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest. 2015 Mar 2;125(3):1215-27

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory