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Sequence Detail
P10085 Q8C6B1 (UniProt | EBI) Last sequence update: 2011-07-27
Last annotation update: 2019-05-08
from provider
RecName: Full=Myoblast determination protein 1;
Polypeptide 318 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Myod1 myogenic differentiation 1 106 141 9 12
Sequence references in MGI J:2348 Zingg JM, et al., Characterisation of a genomic clone covering the structural mouse MyoD1 gene and its promoter region. Nucleic Acids Res. 1991 Dec 11;19(23):6433-9
J:9415 Tapscott SJ, et al., MyoD1: a nuclear phosphoprotein requiring a Myc homology region to convert fibroblasts to myoblasts. Science. 1988 Oct 21;242(4877):405-11
J:20067 Davis RL, et al., Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell. 1987 Dec 24;51(6):987-1000
J:42828 Pinney DF, et al., Myogenic lineage determination and differentiation: evidence for a regulatory gene pathway. Cell. 1988 Jun 3;53(5):781-93
J:87212 Hamamori Y, et al., The basic domain of myogenic basic helix-loop-helix (bHLH) proteins is the novel target for direct inhibition by another bHLH protein, Twist. Mol Cell Biol. 1997 Nov;17(11):6563-73
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:153063 Sambasivan R, et al., The small chromatin-binding protein p8 coordinates the association of anti-proliferative and pro-myogenic proteins at the myogenin promoter. J Cell Sci. 2009 Oct 1;122(Pt 19):3481-91
J:165945 Bruscoli S, et al., Glucocorticoid-induced leucine zipper (GILZ) and long GILZ inhibit myogenic differentiation and mediate anti-myogenic effects of glucocorticoids. J Biol Chem. 2010 Apr 2;285(14):10385-96
J:177741 Eom GH, et al., Histone methyltransferase SETD3 regulates muscle differentiation. J Biol Chem. 2011 Oct 7;286(40):34733-42
J:182387 Caretti G, et al., The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation. Dev Cell. 2006 Oct;11(4):547-60
J:204624 Harada A, et al., Chd2 interacts with H3.3 to determine myogenic cell fate. EMBO J. 2012 Jun 29;31(13):2994-3007
J:228418 Simone C, et al., Activation of MyoD-dependent transcription by cdk9/cyclin T2. Oncogene. 2002 Jun 13;21(26):4137-48
J:243401 Wilson EM, et al., Control of MyoD function during initiation of muscle differentiation by an autocrine signaling pathway activated by insulin-like growth factor-II. J Biol Chem. 2006 Oct 06;281(40):29962-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory