Sequence Detail

ID/Version

P0C605 Q14DK6 Q9Z0Z0 (UniProt | EBI)

Last sequence update: 2008-01-15
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=cGMP-dependent protein kinase 1; Short=cGK 1; Short=cGK1; EC=2.7.11.12;AltName: Full=cGMP-dependent protein kinase I; Short=cGKI;

Provider

SWISS-PROT

Sequence

Polypeptide 671 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prkg1	protein kinase, cGMP-dependent, type I	53	105	4	20

Sequence references in MGI

J:48058 Pfeifer A, et al., Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO J. 1998 Jun 1;17(11):3045-51
J:52526 Hall KU, et al., Phosphorylation-dependent inhibition of protein phosphatase-1 by G-substrate. A Purkinje cell substrate of the cyclic GMP-dependent protein kinase. J Biol Chem. 1999 Feb 5;274(6):3485-95
J:53887 Collins SP, et al., Cyclic AMP- and cyclic GMP-dependent protein kinases differ in their regulation of cyclic AMP response element-dependent gene transcription. J Biol Chem. 1999 Mar 26;274(13):8391-404
J:54479 Massberg S, et al., Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I. J Exp Med. 1999 Apr 19;189(8):1255-64
J:144971 Langmesser S, et al., cGMP-dependent protein kinase type I is implicated in the regulation of the timing and quality of sleep and wakefulness. PLoS One. 2009;4(1):e4238
J:180467 Antl M, et al., IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation. Blood. 2007 Jan 15;109(2):552-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89