Sequence Detail

ID/Version

P09838 Q99PD0 Q99PD1 (UniProt | EBI)

Last sequence update: 2018-12-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=DNA nucleotidylexotransferase; EC=2.7.7.31 {ECO:0000269|PubMed:11938351, ECO:0000269|PubMed:23856622, ECO:0000269|PubMed:23968551}; EC=3.1.11.- {ECO:0000269|PubMed:11938351};AltName: Full=Terminal addition enzyme;AltName: Ful

Provider

SWISS-PROT

Sequence

Polypeptide 510 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dntt	deoxynucleotidyltransferase, terminal	46	105	3	12

Sequence references in MGI

J:4640 Doyen N, et al., Differential splicing in mouse thymus generates two forms of terminal deoxynucleotidyl transferase. Nucleic Acids Res. 1993 Mar 11;21(5):1187-91
J:64571 Boule JB, et al., Comparison of the two murine deoxynucleotidyltransferase terminal isoforms. A 20-AMINO ACID INSERTION IN THE HIGHLY CONSERVED CARBOXYL-TERMINAL REGION MODIFIES THE THERMOSENSITIVITY BUT NOT THE CATALYTIC ACTIVITY. J Biol Chem. 2000 Sep 15;275(37):28984-8
J:76238 Thai TH, et al., Distinct and opposite diversifying activities of terminal transferase splice variants. Nat Immunol. 2002 May;3(5):457-62
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:134391 Benedict CL, et al., The long isoform of terminal deoxynucleotidyl transferase enters the nucleus and, rather than catalyzing nontemplated nucleotide addition, modulates the catalytic activity of the short isoform. J Exp Med. 2001 Jan 1;193(1):89-99
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89