Sequence Detail

ID/Version

P09528 Q3UI44 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Ferritin heavy chain; Short=Ferritin H subunit; EC=1.16.3.1 {ECO:0000250|UniProtKB:P02794};Contains: RecName: Full=Ferritin heavy chain, N-terminally processed;

Provider

SWISS-PROT

Sequence

Polypeptide 182 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fth1	ferritin heavy polypeptide 1	34	102	4	20

Sequence references in MGI

J:9319 Torti SV, et al., The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene. J Biol Chem. 1988 Sep 5;263(25):12638-44
J:9732 Beaumont C, et al., Transcriptional regulation of ferritin H and L subunits in adult erythroid and liver cells from the mouse. Unambiguous identification of mouse ferritin subunits and in vitro formation of the ferritin shells. J Biol Chem. 1989 May 5;264(13):7498-504
J:10066 Yachou AK, et al., Nucleotide sequence of the mouse ferritin H chain gene. Nucleic Acids Res. 1989 Oct 11;17(19):8005
J:20093 Miyazaki Y, et al., Nucleotide sequence of cDNA encoding the heavy subunit of mouse macrophage ferritin. Nucleic Acids Res. 1988 Nov 11;16(21):10373
J:28598 Kwak EL, et al., Murine ferritin heavy chain: isolation and characterization of a functional gene. Gene. 1990 Oct 15;94(2):255-61
J:60287 Ferreira C, et al., Early embryonic lethality of H ferritin gene deletion in mice. J Biol Chem. 2000 Feb 4;275(5):3021-4
J:70685 Ferreira C, et al., H ferritin knockout mice: a model of hyperferritinemia in the absence of iron overload. Blood. 2001 Aug 1;98(3):525-32
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:144982 Li JY, et al., Scara5 is a ferritin receptor mediating non-transferrin iron delivery. Dev Cell. 2009 Jan;16(1):35-46
J:217701 Dowdle WE, et al., Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014 Nov;16(11):1069-79
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89