Sequence Detail

ID/Version

P08923 A2AQ22 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Leukocyte tyrosine kinase receptor {ECO:0000303|PubMed:2357970}; EC=2.7.10.1 {ECO:0000250|UniProtKB:P29376, ECO:0000255|PROSITE-ProRule:PRU10028};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 888 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ltk	leukocyte tyrosine kinase	36	103	3	7

Sequence references in MGI

J:1870 Haase VH, et al., Alternatively spliced ltk mRNA in neurons predicts a receptor with a larger putative extracellular domain. Oncogene. 1991 Dec;6(12):2319-25
J:3712 Snijders AJ, et al., Four tissue-specific mouse ltk mRNAs predict tyrosine kinases that differ upstream of their transmembrane segment. Oncogene. 1993 Jan;8(1):27-35
J:9195 Ben-Neriah Y, et al., Leukocytes express a novel gene encoding a putative transmembrane protein-kinase devoid of an extracellular domain. Nature. 1988 Jun 16;333(6174):672-6
J:33070 Bernards A, et al., The ltk receptor tyrosine kinase is expressed in pre-B lymphocytes and cerebral neurons and uses a non-AUG translational initiator. EMBO J. 1990 Jul;9(7):2279-87
J:87690 Li N, et al., Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus. Hum Mol Genet. 2004 Jan 15;13(2):171-9
J:226591 Weiss JB, et al., Anaplastic lymphoma kinase and leukocyte tyrosine kinase: functions and genetic interactions in learning, memory and adult neurogenesis. Pharmacol Biochem Behav. 2012 Jan;100(3):566-74