Sequence Detail

ID/Version

P08508 (UniProt | EBI)

Last sequence update: 1988-08-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Low affinity immunoglobulin gamma Fc region receptor III; Short=IgG Fc receptor III;AltName: Full=Fc-gamma RIII; Short=FcRIII;AltName: CD_antigen=CD16;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 261 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fcgr3	Fc receptor, IgG, low affinity III	36	100	3	21

Sequence references in MGI

J:8467 Ravetch JV, et al., Structural heterogeneity and functional domains of murine immunoglobulin G Fc receptors. Science. 1986 Nov 7;234(4777):718-25
J:19989 Feinman R, et al., PU.1 and an HLH family member contribute to the myeloid-specific transcription of the Fc gamma RIIIA promoter. EMBO J. 1994 Aug 15;13(16):3852-60
J:123354 Hirano M, et al., IgEb immune complexes activate macrophages through FcgammaRIV binding. Nat Immunol. 2007 Jul;8(7):762-71
J:130906 Jakus Z, et al., Critical but overlapping role of FcgammaRIII and FcgammaRIV in activation of murine neutrophils by immobilized immune complexes. J Immunol. 2008 Jan 1;180(1):618-29