Sequence Detail

ID/Version

P08414 Q61381 (UniProt | EBI)

Last sequence update: 1993-04-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Calcium/calmodulin-dependent protein kinase type IV; Short=CaMK IV; EC=2.7.11.17;AltName: Full=CaM kinase-GR;

Provider

SWISS-PROT

Sequence

Polypeptide 469 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Camk4	calcium/calmodulin-dependent protein kinase IV	58	103	3	11

Sequence references in MGI

J:11438 Jones DA, et al., cDNA sequence and differential expression of the mouse Ca2+/calmodulin-dependent protein kinase IV gene. FEBS Lett. 1991 Sep 2;289(1):105-9
J:32614 Sikela JM, et al., Screening an expression library with a ligand probe: isolation and sequence of a cDNA corresponding to a brain calmodulin-binding protein. Proc Natl Acad Sci U S A. 1987 May;84(9):3038-42
J:70570 Wu JY, et al., Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4. Nat Genet. 2000 Aug;25(4):448-52
J:71846 Kang H, et al., An important role of neural activity-dependent CaMKIV signaling in the consolidation of long-term memory. Cell. 2001 Sep 21;106(6):771-83
J:75854 Wu H, et al., Regulation of Mitochondrial Biogenesis in Skeletal Muscle by CaMK. Science. 2002 Apr 12;296(5566):349-52
J:141817 Fukushima H, et al., Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging. J Neurosci. 2008 Oct 1;28(40):9910-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89