Sequence Detail

ID/Version

P06876 Q61929 E9QMG8 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transcriptional activator Myb;AltName: Full=Proto-oncogene c-Myb;

Provider

SWISS-PROT

Sequence

Polypeptide 636 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Myb	myeloblastosis oncogene	97	128	3	26

Sequence references in MGI

J:8278 Bender TP, et al., Murine myb protooncogene mRNA: cDNA sequence and evidence for 5' heterogeneity. Proc Natl Acad Sci U S A. 1986 May;83(10):3204-8
J:8373 Lavu S, et al., Structural organization and nucleotide sequence of mouse c-myb oncogene: activation in ABPL tumors is due to viral integration in an intron which results in the deletion of the 5' coding sequences. Nucleic Acids Res. 1986 Jul 11;14(13):5309-20
J:10177 Sobieszczuk PW, et al., Structure and biological activity of the transcriptional initiation sequences of the murine c-myb oncogene. Nucleic Acids Res. 1989 Dec 11;17(23):9593-611
J:17641 Gonda TJ, et al., Nucleotide sequence of cDNA clones of the murine myb proto-oncogene. EMBO J. 1985 Aug;4(8):2003-8
J:74346 Tahirov TH, et al., Mechanism of c-Myb-C/EBP beta cooperation from separated sites on a promoter. Cell. 2002 Jan 11;108(1):57-70
J:89440 Kanei-Ishii C, et al., Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK. Genes Dev. 2004 Apr 1;18(7):816-29
J:107109 Morita Y, et al., TRAF7 sequesters c-Myb to the cytoplasm by stimulating its sumoylation. Mol Biol Cell. 2005 Nov;16(11):5433-44
J:125265 Peng S, et al., c-Maf interacts with c-Myb to down-regulate Bcl-2 expression and increase apoptosis in peripheral CD4 cells. Eur J Immunol. 2007 Oct;37(10):2868-80