Sequence Detail

ID/Version

P06745 Q3UZJ1 Q5RJI3 Q9JM07 Q3TEE7 Q3TW50 Q8C675 Q3UUX1 Q3UY84 O89062 (UniProt | EBI)

Last sequence update: 2007-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Glucose-6-phosphate isomerase {ECO:0000303|PubMed:7545951}; Short=GPI {ECO:0000303|PubMed:7545951}; EC=5.3.1.9 {ECO:0000269|PubMed:2344351, ECO:0000269|PubMed:8417789};AltName: Full=Autocrine motility factor {ECO:0000303|PubM

Provider

SWISS-PROT

Sequence

Polypeptide 558 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gpi1	glucose-6-phosphate isomerase 1	75	104	4	29

Sequence references in MGI

J:9102 Faik P, et al., Mouse glucose-6-phosphate isomerase and neuroleukin have identical 3' sequences. Nature. 1988 Mar 31;332(6163):455-7
J:10520 Pretsch W, et al., Glucose phosphate isomerase enzyme-activity mutants in Mus musculus: genetical and biochemical characterization. Biochem Genet. 1990 Feb;28(1-2):97-110
J:18303 Faik P, et al., Identification of a novel tandemly repeated sequence present in an intron of the glucose phosphate isomerase (GPI) gene in mouse and man. Genomics. 1994 May 1;21(1):122-7
J:25187 Gurney ME, et al., Molecular cloning and expression of neuroleukin, a neurotrophic factor for spinal and sensory neurons. Science. 1986 Oct 31;234(4776):566-74
J:35956 Merkle S, et al., Glucose-6-phosphate isomerase deficiency associated with nonspherocytic hemolytic anemia in the mouse: an animal model for the human disease. Blood. 1993 Jan 1;81(1):206-13
J:36586 Kelly A, et al., Genetic evidence that glycolysis is necessary for gastrulation in the mouse. Dev Dyn. 1996 Nov;207(3):300-8
J:62630 Chu CC, et al., Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis. Mol Immunol. 1998 Jun;35(8):487-502
J:92566 Graham Solomons JT, et al., The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening. J Mol Biol. 2004 Sep 17;342(3):847-60
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100999 Giannakopoulos NV, et al., Proteomic identification of proteins conjugated to ISG15 in mouse and human cells. Biochem Biophys Res Commun. 2005 Oct 21;336(2):496-506
J:203030 Buehr M, et al., An electrophoretically detectable modification of glucosephosphate isomerase in mouse spermatozoa. J Reprod Fertil. 1981 Sep;63(1):169-73
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89