Sequence Detail

ID/Version

P05125 Q5FW59 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Natriuretic peptides A {ECO:0000303|PubMed:8760210};AltName: Full=Atrial natriuretic factor prohormone {ECO:0000250|UniProtKB:P01160}; Short=preproANF {ECO:0000250|UniProtKB:P01161}; Short=proANF {ECO:0000303|PubMed:6542248};

Provider

SWISS-PROT

Sequence

Polypeptide 152 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nppa	natriuretic peptide type A	65	175	3	13

Sequence references in MGI

J:7667 Seidman CE, et al., Nucleotide sequences of the human and mouse atrial natriuretic factor genes. Science. 1984 Dec 7;226(4679):1206-9
J:96458 Chan JC, et al., Hypertension in mice lacking the proatrial natriuretic peptide convertase corin. Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):785-90
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:113046 John SW, et al., Blood pressure and fluid-electrolyte balance in mice with reduced or absent ANP. Am J Physiol. 1996 Jul;271(1 Pt 2):R109-14
J:183869 Cui Y, et al., Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy. Nature. 2012 Apr 12;484(7393):246-50
J:183978 Wu F, et al., Processing of pro-atrial natriuretic peptide by corin in cardiac myocytes. J Biol Chem. 2002 May 10;277(19):16900-5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:307725 Madhani M, et al., Vascular natriuretic peptide receptor-linked particulate guanylate cyclases are modulated by nitric oxide-cyclic GMP signalling. Br J Pharmacol. 2003 Aug;139(7):1289-96