Sequence Detail

ID/Version

P04187 (UniProt | EBI)

Last sequence update: 1987-03-20
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Granzyme B(G,H); EC=3.4.21.79 {ECO:0000269|PubMed:35705808};AltName: Full=CTLA-1;AltName: Full=Cytotoxic cell protease 1; Short=CCP1;AltName: Full=Fragmentin-2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 247 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gzmb	granzyme B	47	99	9	16

Sequence references in MGI

J:8372 Brunet JF, et al., The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14. Nature. 1986 Jul 17-23;322(6076):268-71
J:18647 Ko MS, et al., Genetic mapping of 40 cDNA clones on the mouse genome by PCR. Mamm Genome. 1994 Jun;5(6):349-55
J:22959 Lobe CG, et al., Novel serine proteases encoded by two cytotoxic T lymphocyte-specific genes. Science. 1986 May 16;232(4752):858-61
J:24188 Lobe CG, et al., Organization of two genes encoding cytotoxic T lymphocyte-specific serine proteases CCPI and CCPII. Biochemistry. 1988 Sep 6;27(18):6941-6
J:39247 Masson D, et al., A family of serine esterases in lytic granules of cytolytic T lymphocytes. Cell. 1987 Jun 5;49(5):679-85
J:326897 Nozaki K, et al., Caspase-7 activates ASM to repair gasdermin and perforin pores. Nature. 2022 Jun;606(7916):960-967