Sequence Detail

ID/Version

P02535 Q8BUX3 Q8BVU3 Q9JKB4 Q8BV09 P08731 Q9CXH6 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Keratin, type I cytoskeletal 10;AltName: Full=56 kDa cytokeratin;AltName: Full=Cytokeratin-10; Short=CK-10;AltName: Full=Keratin, type I cytoskeletal 59 kDa;AltName: Full=Keratin-10; Short=K10;

Provider

SWISS-PROT

Sequence

Polypeptide 570 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Krt10	keratin 10	38	149	10	22

Sequence references in MGI

J:7867 Krieg TM, et al., Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene. J Biol Chem. 1985 May 25;260(10):5867-70
J:16017 Steinert PM, et al., Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments. Nature. 1983 Apr 28;302(5911):794-800
J:76311 Peters B, et al., Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex. Mol Biol Cell. 2001 Jun;12(6):1775-89
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:214772 Fischer H, et al., Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation. J Invest Dermatol. 2014 Oct;134(10):2579-88
J:252645 Fischer H, et al., Keratins K2 and K10 are essential for the epidermal integrity of plantar skin. J Dermatol Sci. 2016 Jan;81(1):10-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87
J:322687 Bouameur JE, et al., Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure. J Invest Dermatol. 2014 Nov;134(11):2776-2783