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Sequence Detail
ID/Version
P01575 (UniProt | EBI) Last sequence update: 1986-07-21
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Interferon beta {ECO:0000303|PubMed:2726460, ECO:0000303|PubMed:6688252}; Short=IFN-beta {ECO:0000303|PubMed:2726460};Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 182 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ifnb1 interferon beta 1, fibroblast 56 102 4 20
Sequence references in MGI J:7139 Higashi Y, et al., Structure and expression of a cloned cDNA for mouse interferon-beta. J Biol Chem. 1983 Aug 10;258(15):9522-9
J:9811 Kuga T, et al., Nucleotide sequence of the mouse interferon-beta gene. Nucleic Acids Res. 1989 Apr 25;17(8):3291
J:26747 Vodjdani G, et al., Structure and characterization of a murine chromosomal fragment containing the interferon beta gene. J Mol Biol. 1988 Nov 20;204(2):221-31
J:61048 Deonarain R, et al., Impaired antiviral response and alpha/beta interferon induction in mice lacking beta interferon. J Virol. 2000 Apr;74(7):3404-9
J:83021 Teige I, et al., IFN-beta Gene Deletion Leads to Augmented and Chronic Demyelinating Experimental Autoimmune Encephalomyelitis. J Immunol. 2003 May 1;170(9):4776-84
J:86527 Deonarain R, et al., Critical roles for IFN-beta in lymphoid development, myelopoiesis, and tumor development: links to tumor necrosis factor alpha. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13453-8
J:208239 de Weerd NA, et al., Structural basis of a unique interferon-beta signaling axis mediated via the receptor IFNAR1. Nat Immunol. 2013 Sep;14(9):901-7
J:226090 Ejlerskov P, et al., Lack of Neuronal IFN-beta-IFNAR Causes Lewy Body- and Parkinson's Disease-like Dementia. Cell. 2015 Oct 8;163(2):324-39

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory