Sequence Detail

ID/Version

P01101 (UniProt | EBI)

Last sequence update: 1986-07-21
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Protein c-Fos {ECO:0000305};AltName: Full=Cellular oncogene fos;AltName: Full=FBJ osteosarcoma oncogene {ECO:0000312|MGI:MGI:95574};AltName: Full=Transcription factor AP-1 subunit c-Fos {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 380 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fos	FBJ osteosarcoma oncogene	149	135	4	32

Sequence references in MGI

J:7042 Van Beveren C, et al., Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini. Cell. 1983 Apr;32(4):1241-55
J:78465 Murphy LO, et al., Molecular interpretation of ERK signal duration by immediate early gene products. Nat Cell Biol. 2002 Aug;4(8):556-64
J:85755 Monje P, et al., Phosphorylation of the carboxyl-terminal transactivation domain of c-Fos by extracellular signal-regulated kinase mediates the transcriptional activation of AP-1 and cellular transformation induced by platelet-derived growth factor. Mol Cell Biol. 2003 Oct;23(19):7030-43
J:96755 David JP, et al., Essential role of RSK2 in c-Fos-dependent osteosarcoma development. J Clin Invest. 2005 Mar;115(3):664-72
J:254428 Vierbuchen T, et al., AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection. Mol Cell. 2017 Dec 21;68(6):1067-1082.e12