Sequence Detail

ID/Version

P01029 Q61859 Q61372 Q31201 Q3TYY1 Q3TZC9 Q6NWV8 O70346 E9QKK7 Q62353 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Complement C4-B;Contains: RecName: Full=Complement C4 beta chain;Contains: RecName: Full=Complement C4 alpha chain;Contains: RecName: Full=C4a anaphylatoxin;Contains: RecName: Full=Complement C4 gamma chain;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1738 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	C4b	complement C4B (Chido blood group)	27	102	7	8

Sequence references in MGI

J:7151 Ogata RT, et al., cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4). Proc Natl Acad Sci U S A. 1983 Aug;80(16):5061-5
J:7633 Nonaka M, et al., Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein. Proc Natl Acad Sci U S A. 1984 Nov;81(21):6822-6
J:7795 Levi-Strauss M, et al., Multiple duplications of complement C4 gene correlate with H-2-controlled testosterone-independent expression of its sex-limited isoform, C4-Slp. Proc Natl Acad Sci U S A. 1985 Mar;82(6):1746-50
J:8004 Sepich DS, et al., Complete cDNA sequence of the fourth component of murine complement. Proc Natl Acad Sci U S A. 1985 Sep;82(17):5895-9
J:8067 Nonaka M, et al., Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp. Immunol Rev. 1985 Oct;87:81-99
J:10006 Ogata RT, et al., Sequence of the gene for murine complement component C4. J Biol Chem. 1989 Oct 5;264(28):16565-72
J:15369 Tosi M, et al., Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component. Philos Trans R Soc Lond B Biol Sci. 1984 Sep 6;306(1129):389-94
J:32275 Nonaka M, et al., Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects. J Biol Chem. 1985 Sep 15;260(20):10936-43
J:68219 Nonaka M, et al., Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes. Proc Natl Acad Sci U S A. 1986 Oct;83(20):7883-7
J:68220 Hemenway C, et al., Sequence comparison of alleles of the fourth component of complement (C4) and sex-limited protein (Slp). Nucleic Acids Res. 1986 Mar 25;14(6):2539-54
J:86796 Xie T, et al., Analysis of the gene-dense Major Histocompatibility Complex class III region and its comparison to mouse. Genome Res. 2003 Dec;13(12):2621-36
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89