Sequence Detail

ID/Version

O89023 Q543Q8 Q9QUS7 (UniProt | EBI)

Last sequence update: 2000-12-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Tripeptidyl-peptidase 1; Short=TPP-1; EC=3.4.14.9 {ECO:0000269|PubMed:28464005};AltName: Full=Lysosomal pepstatin-insensitive protease; Short=LPIC;AltName: Full=Tripeptidyl aminopeptidase;AltName: Full=Tripeptidyl-pep

Provider

SWISS-PROT

Sequence

Polypeptide 562 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tpp1	tripeptidyl peptidase I	72	104	3	12

Sequence references in MGI

J:53295 Katz ML, et al., Characterization and chromosomal mapping of a mouse ortholog of the late-infantile ceroid-lipofuscinosis gene CLN2. Mamm Genome. 1999 Nov;10(11):1050-3
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:235261 Lyly A, et al., Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins. BMC Cell Biol. 2009;10:83
J:241344 Geraets RD, et al., A tailored mouse model of CLN2 disease: A nonsense mutant for testing personalized therapies. PLoS One. 2017;12(5):e0176526
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89