Sequence Detail

ID/Version

O88939 B7ZNL6 B2RRP7 Q3U372 Q9CRJ0 (UniProt | EBI)

Last sequence update: 2008-09-02
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Zinc finger and BTB domain-containing protein 7A {ECO:0000305};AltName: Full=Leukemia/lymphoma-related factor {ECO:0000303|PubMed:9927193};AltName: Full=POZ and Krueppel erythroid myeloid ontogenic factor {ECO:0000303|PubMed:15662416};

Provider

SWISS-PROT

Sequence

Polypeptide 569 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Zbtb7a	zinc finger and BTB domain containing 7a	68	104	3	73

Sequence references in MGI

J:52528 Davies JM, et al., Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogene. Oncogene. 1999 Jan 14;18(2):365-75
J:88741 Laudes M, et al., Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis. J Biol Chem. 2004 Mar 19;279(12):11711-8
J:95884 Maeda T, et al., Role of the proto-oncogene Pokemon in cellular transformation and ARF repression. Nature. 2005 Jan 20;433(7023):278-85
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114110 Liu CJ, et al., Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. J Biol Chem. 2004 Nov 5;279(45):47081-91
J:121576 Maeda T, et al., Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF. Science. 2007 May 11;316(5826):860-6
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:227643 Liu XS, et al., LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair. Nat Commun. 2015;6:8325
J:245247 Masuda T, et al., Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin. Science. 2016 Jan 15;351(6270):285-9
J:272425 Ramos Pittol JM, et al., Zbtb7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors. PLoS Biol. 2018 May;16(5):e2004526
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89