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Sequence Detail
ID/Version
O88909 Q8CCX3 Q3TZF9 Q91WJ9 Q8CFH5 (UniProt | EBI) Last sequence update: 2007-01-23
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=Organic anion transporter 3 {ECO:0000303|PubMed:15075193, ECO:0000303|PubMed:15100168}; Short=mOat3 {ECO:0000303|PubMed:15100168};AltName: Full=Organic anion/dicarboxylate exchanger;AltName: Full=Reduced in osteosclerosis transporter
Provider SWISS-PROT
Sequence
Polypeptide 537 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Slc22a8 solute carrier family 22 (organic anion transporter), member 8 26 106 3 6
Sequence references in MGI J:54028 Brady KP, et al., A novel putative transporter maps to the osteosclerosis (oc) mutation and is not expressed in the oc mutant mouse. Genomics. 1999 Mar 15;56(3):254-61
J:78014 Sweet DH, et al., Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. J Biol Chem. 2002 Jul 26;277(30):26934-43
J:95429 Sykes D, et al., Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice. Am J Physiol Renal Physiol. 2004 May;286(5):F972-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:105002 Bahn A, et al., Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites. Am J Physiol Cell Physiol. 2005 Nov;289(5):C1075-84
J:195413 Breljak D, et al., Sex-dependent expression of Oat3 (Slc22a8) and Oat1 (Slc22a6) proteins in murine kidneys. Am J Physiol Renal Physiol. 2013 Apr;304(8):F1114-26
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory