Sequence Detail

ID/Version

O88879 A2RRK8 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Apoptotic protease-activating factor 1; Short=APAF-1;

Provider

SWISS-PROT

Sequence

Polypeptide 1249 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Apaf1	apoptotic peptidase activating factor 1	45	109	3	19

Sequence references in MGI

J:49840 Cecconi F, et al., Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell. 1998 Sep 18;94(6):727-37
J:93333 Sakai T, et al., Nucling recruits Apaf-1/pro-caspase-9 complex for the induction of stress-induced apoptosis. J Biol Chem. 2004 Oct 24;279(39):41131-40
J:93353 Cho DH, et al., Induced inhibition of ischemic/hypoxic injury by APIP, a novel Apaf-1-interacting protein. J Biol Chem. 2004 Oct 17;279(38):39942-50
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89