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Sequence Detail
ID/Version
O88829 B2RRS1 Q91YF2 Q91YF3 Q9QWF8 Q9CZ65 Q3TY01 Q3TMT6 Q9QWF9 (UniProt | EBI) Last sequence update: 2008-05-20
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=Lactosylceramide alpha-2,3-sialyltransferase; EC=2.4.3.9 {ECO:0000269|PubMed:10092602, ECO:0000269|PubMed:12629211, ECO:0000269|PubMed:9875239};AltName: Full=CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase;AltName: Full=Gangli
Provider SWISS-PROT
Sequence
Polypeptide 414 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 6 99 3 8
Sequence references in MGI J:54025 Fukumoto S, et al., Expression cloning of mouse cDNA of CMP-NeuAc:Lactosylceramide alpha2,3-sialyltransferase, an enzyme that initiates the synthesis of gangliosides. J Biol Chem. 1999 Apr 2;274(14):9271-6
J:55319 Kono M, et al., Molecular cloning and functional expression of a fifth-type alpha 2,3-sialyltransferase (mST3Gal V: GM3 synthase). Biochem Biophys Res Commun. 1998 Dec 9;253(1):170-5
J:82723 Yamashita T, et al., Enhanced insulin sensitivity in mice lacking ganglioside GM3. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3445-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:229230 Tsukamoto K, et al., Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins. J Biol Chem. 2005 Oct 21;280(42):35164-71

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory