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Sequence Detail
O88829 Q9CZ65 Q9QWF8 Q9QWF9 Q91YF2 Q3TMT6 Q3TY01 B2RRS1 Q91YF3 (UniProt | EBI) Last sequence update: 2008-05-20
Last annotation update: 2018-10-10
from provider
RecName: Full=Lactosylceramide alpha-2,3-sialyltransferase; EC=;AltName: Full=CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase;AltName: Full=Ganglioside GM3 synthase;AltName: Full=ST3Gal V; Short=ST3GalV;AltName: Full=Sialylt
Polypeptide 414 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 12 3 9 5
Sequence references in MGI J:54025 Fukumoto S, et al., Expression cloning of mouse cDNA of CMP-NeuAc:Lactosylceramide alpha2,3-sialyltransferase, an enzyme that initiates the synthesis of gangliosides. J Biol Chem. 1999 Apr 2;274(14):9271-6
J:55319 Kono M, et al., Molecular cloning and functional expression of a fifth-type alpha 2,3-sialyltransferase (mST3Gal V: GM3 synthase). Biochem Biophys Res Commun. 1998 Dec 9;253(1):170-5
J:82723 Yamashita T, et al., Enhanced insulin sensitivity in mice lacking ganglioside GM3. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3445-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:229230 Tsukamoto K, et al., Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins. J Biol Chem. 2005 Oct 21;280(42):35164-71

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last database update
MGI 6.13
The Jackson Laboratory