Sequence Detail

ID/Version

O88829 B2RRS1 Q3TY01 Q91YF3 Q9CZ65 Q3TMT6 Q91YF2 Q9QWF8 Q9QWF9 (UniProt | EBI)

Last sequence update: 2008-05-20
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Lactosylceramide alpha-2,3-sialyltransferase; EC=2.4.3.9 {ECO:0000269|PubMed:10092602, ECO:0000269|PubMed:12629211, ECO:0000269|PubMed:9875239};AltName: Full=CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase;AltName: Full=Gangli

Provider

SWISS-PROT

Sequence

Polypeptide 414 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	St3gal5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	14	100	3	8

Sequence references in MGI

J:54025 Fukumoto S, et al., Expression cloning of mouse cDNA of CMP-NeuAc:Lactosylceramide alpha2,3-sialyltransferase, an enzyme that initiates the synthesis of gangliosides. J Biol Chem. 1999 Apr 2;274(14):9271-6
J:55319 Kono M, et al., Molecular cloning and functional expression of a fifth-type alpha 2,3-sialyltransferase (mST3Gal V: GM3 synthase). Biochem Biophys Res Commun. 1998 Dec 9;253(1):170-5
J:82723 Yamashita T, et al., Enhanced insulin sensitivity in mice lacking ganglioside GM3. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3445-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:229230 Tsukamoto K, et al., Binding of Clostridium botulinum type C and D neurotoxins to ganglioside and phospholipid. Novel insights into the receptor for clostridial neurotoxins. J Biol Chem. 2005 Oct 21;280(42):35164-71