Sequence Detail

ID/Version

O88623 Q6X4T9 Q8VD74 Q6X4U1 Q9JJ87 (UniProt | EBI)

Last sequence update: 2022-12-14
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Ubiquitin carboxyl-terminal hydrolase 2 {ECO:0000305}; EC=3.4.19.12;AltName: Full=41 kDa ubiquitin-specific protease;AltName: Full=Deubiquitinating enzyme 2;AltName: Full=Ubiquitin thioesterase 2;AltName: Full=Ubiquitin-specific-proc

Provider

SWISS-PROT

Sequence

Polypeptide 619 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Usp2	ubiquitin specific peptidase 2	39	109	4	14

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:108694 Gousseva N, et al., Gene structure, alternate splicing, tissue distribution, cellular localization, and developmental expression pattern of mouse deubiquitinating enzyme isoforms Usp2-45 and Usp2-69. Gene Expr. 2003;11(3-4):163-79
J:215857 Yang Y, et al., Regulation of behavioral circadian rhythms and clock protein PER1 by the deubiquitinating enzyme USP2. Biol Open. 2012 Aug 15;1(8):789-801
J:243462 Pouly D, et al., USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level. PLoS One. 2016;11(1):e0145155
J:295456 Yang Y, et al., USP2 regulates the intracellular localization of PER1 and circadian gene expression. J Biol Rhythms. 2014 Aug;29(4):243-56