Sequence Detail

ID/Version

O88531 Q9D681 Q9WTY3 (UniProt | EBI)

Last sequence update: 2002-03-05
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Palmitoyl-protein thioesterase 1; Short=PPT-1; EC=3.1.2.2 {ECO:0000250|UniProtKB:P50897}; EC=3.1.2.22 {ECO:0000250|UniProtKB:P50897};AltName: Full=Palmitoyl-protein hydrolase 1;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 306 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ppt1	palmitoyl-protein thioesterase 1	118	104	3	16

Sequence references in MGI

J:49059 Salonen T, et al., Mouse palmitoyl protein thioesterase: gene structure and expression of cDNA. Genome Res. 1998 Jul;8(7):724-30
J:54950 Zhang Z, et al., Palmitoyl-protein thioesterase gene expression in the developing mouse brain and retina: implications for early loss of vision in infantile neuronal ceroid lipofuscinosis. Gene. 1999 Apr 29;231(1-2):203-11
J:72931 Gupta P, et al., Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13566-71
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:235261 Lyly A, et al., Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins. BMC Cell Biol. 2009;10:83
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89