Sequence Detail

ID/Version

O88487 Q3TGH7 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Cytoplasmic dynein 1 intermediate chain 2;AltName: Full=Cytoplasmic dynein intermediate chain 2;AltName: Full=Dynein intermediate chain 2, cytosolic; Short=DH IC-2;

Provider

SWISS-PROT

Sequence

Polypeptide 612 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dync1i2	dynein cytoplasmic 1 intermediate chain 2	22	135	4	62

Sequence references in MGI

J:53212 Crackower MA, et al., Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human. Genomics. 1999 Feb 1;55(3):257-67
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:200276 Splinter D, et al., BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures. Mol Biol Cell. 2012 Nov;23(21):4226-41
J:242894 Lehti MS, et al., SPEF2 functions in microtubule-mediated transport in elongating spermatids to ensure proper male germ cell differentiation. Development. 2017 Jul 15;144(14):2683-2693
J:245166 Chanduri M, et al., Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport. Biochem J. 2016 Oct 01;473(19):3031-47
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:319365 Liu S, et al., CFAP61 is required for sperm flagellum formation and male fertility in human and mouse. Development. 2021 Dec 1;148(23):dev199805