Sequence Detail

ID/Version

O88455 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=7-dehydrocholesterol reductase {ECO:0000250|UniProtKB:Q9UBM7}; Short=7-DHC reductase; EC=1.3.1.21 {ECO:0000269|PubMed:11230174};AltName: Full=Cholesterol-5,6-epoxide hydrolase subunit DHCR7 {ECO:0000250|UniProtKB:Q9UBM7};

Provider

SWISS-PROT

Sequence

Polypeptide 471 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dhcr7	7-dehydrocholesterol reductase	39	99	3	9

Sequence references in MGI

J:48735 Fitzky BU, et al., Mutations in the Delta7-sterol reductase gene in patients with the Smith-Lemli-Opitz syndrome. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8181-6
J:68084 Wassif CA, et al., Biochemical, phenotypic and neurophysiological characterization of a genetic mouse model of RSH/Smith--Lemli--Opitz syndrome. Hum Mol Genet. 2001 Mar 15;10(6):555-64
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89