Sequence Detail

ID/Version

O88413 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Tubby-related protein 3 {ECO:0000305};AltName: Full=Tubby-like protein 3;

Provider

SWISS-PROT

Sequence

Polypeptide 460 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tulp3	TUB like protein 3	49	100	3	34

Sequence references in MGI

J:51388 Nishina PM, et al., Molecular characterization of a novel tubby gene family member, TULP3, in mouse and humans. Genomics. 1998 Dec 1;54(2):215-20
J:70060 Ikeda A, et al., Neural tube defects and neuroepithelial cell death in Tulp3 knockout mice. Hum Mol Genet. 2001 Jun 1;10(12):1325-34
J:147574 Norman RX, et al., Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling. Hum Mol Genet. 2009 May 15;18(10):1740-54
J:148411 Cameron DA, et al., Tulp3 is a critical repressor of mouse hedgehog signaling. Dev Dyn. 2009 May;238(5):1140-9
J:153130 Caberoy NB, et al., Unconventional secretion of tubby and tubby-like protein 1. FEBS Lett. 2009 Sep 17;583(18):3057-62
J:168317 Qin J, et al., Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1456-61
J:282613 Hilgendorf KI, et al., Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis. Cell. 2019 Nov 27;179(6):1289-1305.e21