Sequence Detail

ID/Version

O88393 Q6NS72 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transforming growth factor beta receptor type 3; Short=TGF-beta receptor type 3; Short=TGFR-3;AltName: Full=Betaglycan;AltName: Full=Transforming growth factor beta receptor III; Short=TGF-beta receptor type III;Flags

Provider

SWISS-PROT

Sequence

Polypeptide 850 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tgfbr3	transforming growth factor, beta receptor III	113	115	3	18

Sequence references in MGI

J:48601 Ponce-Castaneda MV, et al., Murine betaglycan primary structure, expression and glycosaminoglycan attachment sites. Biochim Biophys Acta. 1998 May 19;1384(2):189-96
J:141344 Compton LA, et al., Coronary vessel development is dependent on the type III transforming growth factor beta receptor. Circ Res. 2007 Oct 12;101(8):784-91
J:178172 Sanchez NS, et al., The cytoplasmic domain of TGFbetaR3 through its interaction with the scaffolding protein, GIPC, directs epicardial cell behavior. Dev Biol. 2011 Oct 15;358(2):331-43
J:203733 Diestel U, et al., Identification of a Novel TGF-beta-Binding Site in the Zona Pellucida C-terminal (ZP-C) Domain of TGF-beta-Receptor-3 (TGFR-3). PLoS One. 2013;8(6):e67214
J:266352 Li Y, et al., Betaglycan (TGFBR3) functions as an inhibin A, but not inhibin B, co-receptor in pituitary gonadotrope cells in mice. Endocrinology. 2018 Oct 25;
J:316383 Brule E, et al., TGFBR3L is an inhibin B co-receptor that regulates female fertility. Sci Adv. 2021;7(51):eabl4391