Sequence Detail

ID/Version

O88174 Q9R0R9 (UniProt | EBI)

Last sequence update: 1998-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Membrane cofactor protein;AltName: CD_antigen=CD46;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 365 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd46	CD46 antigen, complement regulatory protein	30	98	4	7

Sequence references in MGI

J:46287 Tsujimura A, et al., Molecular cloning of a murine homologue of membrane cofactor protein (CD46): preferential expression in testicular germ cells. Biochem J. 1998 Feb 15;330(Pt 1):163-8
J:51088 Miwa T, et al., Molecular cloning of rat and mouse membrane cofactor protein (MCP, CD46): preferential expression in testis and close linkage between the mouse Mcp and Cr2 genes on distal chromosome 1. Immunogenetics. 1998 Nov-Dec;48(6):363-71
J:67188 Nomura M, et al., Membrane and secretory forms of mouse membrane cofactor protein (CD46) generated from a single gene through alternative splicing. Immunogenetics. 1999 Dec;50(5-6):245-54
J:82516 Inoue N, et al., Disruption of mouse CD46 causes an accelerated spontaneous acrosome reaction in sperm. Mol Cell Biol. 2003 Apr;23(7):2614-22
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563