Sequence Detail

ID/Version

O70585 Q9CTZ1 O70563 E9Q0F2 (UniProt | EBI)

Last sequence update: 2011-06-28
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Dystrobrevin beta {ECO:0000305}; Short=DTN-B {ECO:0000303|PubMed:9540997}; Short=mDTN-BDTN-B;AltName: Full=Beta-dystrobrevin {ECO:0000303|PubMed:9419360};

Provider

SWISS-PROT

Sequence

Polypeptide 659 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dtnb	dystrobrevin, beta	40	98	4	84

Sequence references in MGI

J:46808 Puca AA, et al., Identification and characterization of a novel member of the dystrobrevin gene family. FEBS Lett. 1998 Mar 20;425(1):7-13
J:47385 Blake DJ, et al., beta-dystrobrevin, a member of the dystrophin-related protein family. Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):241-6
J:50574 Loh NY, et al., Genomic organization and refined mapping of the mouse beta-dystrobrevin gene. Mamm Genome. 1998 Nov;9(11):857-62
J:70125 Benson MA, et al., Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain. J Biol Chem. 2001 Jun 29;276(26):24232-41
J:76454 Loh NY, et al., Role of beta-dystrobrevin in nonmuscle dystrophin-associated protein complex-like complexes in kidney and liver. Mol Cell Biol. 2001 Nov;21(21):7442-8
J:86976 Macioce P, et al., Beta-dystrobrevin interacts directly with kinesin heavy chain in brain. J Cell Sci. 2003 Dec 1;116(Pt 23):4847-56
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106640 Grady RM, et al., Cerebellar synaptic defects and abnormal motor behavior in mice lacking alpha- and beta-dystrobrevin. J Neurosci. 2006 Mar 15;26(11):2841-51
J:119852 Loh NY, et al., Assembly of multiple dystrobrevin-containing complexes in the kidney. J Cell Sci. 2000 Aug;113(Pt 15):2715-24
J:124778 Ceccarini M, et al., Association of dystrobrevin and regulatory subunit of protein kinase a: a new role for dystrobrevin as a scaffold for signaling proteins. J Mol Biol. 2007 Aug 31;371(5):1174-87
J:201389 Fratini F, et al., Phosphorylation on threonine 11 of beta-dystrobrevin alters its interaction with kinesin heavy chain. FEBS J. 2012 Nov;279(22):4131-44
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:304574 Artegiani B, et al., The interaction with HMG20a/b proteins suggests a potential role for beta-dystrobrevin in neuronal differentiation. J Biol Chem. 2010 Aug 6;285(32):24740-50
J:304707 Veroni C, et al., beta-dystrobrevin, a kinesin-binding receptor, interacts with the extracellular matrix components pancortins. J Neurosci Res. 2007 Sep;85(12):2631-9