Sequence Detail

ID/Version

O70546 Q6DI80 Q7TSG4 A2AID2 (UniProt | EBI)

Last sequence update: 2007-01-09
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Lysine-specific demethylase 6A; EC=1.14.11.68 {ECO:0000250|UniProtKB:O15550};AltName: Full=Histone demethylase UTX;AltName: Full=Ubiquitously transcribed TPR protein on the X chromosome;AltName: Full=Ubiquitously transcribed X chromo

Provider

SWISS-PROT

Sequence

Polypeptide 1401 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kdm6a	lysine (K)-specific demethylase 6A	54	109	4	58

Sequence references in MGI

J:46792 Greenfield A, et al., The UTX gene escapes X inactivation in mice and humans. Hum Mol Genet. 1998 Apr;7(4):737-42
J:166998 Miller SA, et al., Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression. Mol Cell. 2010 Nov 24;40(4):594-605
J:195534 Wang AH, et al., The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis. EMBO J. 2013 Apr 17;32(8):1075-86
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87