Sequence Detail

ID/Version

O70433 P97448 (UniProt | EBI)

Last sequence update: 1998-08-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Four and a half LIM domains protein 2; Short=FHL-2;AltName: Full=Skeletal muscle LIM-protein 3; Short=SLIM-3;

Provider

SWISS-PROT

Sequence

Polypeptide 279 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fhl2	four and a half LIM domains 2	41	121	4	10

Sequence references in MGI

J:53041 Morgan MJ, et al., The LIM proteins FHL1 and FHL3 are expressed differently in skeletal muscle. Biochem Biophys Res Commun. 1999 Feb 16;255(2):245-50
J:63769 Chu P, et al., Expression patterns of FHL/SLIM family members suggest important functional roles in skeletal muscle and cardiovascular system. Mech Dev. 2000 Jul;95(1-2):259-65
J:168863 Shi X, et al., Fhl2 interacts with Foxk1 and corepresses Foxo4 activity in myogenic progenitors. Stem Cells. 2010 Mar 31;28(3):462-9
J:189137 Hojayev B, et al., FHL2 binds calcineurin and represses pathological cardiac growth. Mol Cell Biol. 2012 Oct;32(19):4025-34
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89