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Sequence Detail
O70373 (UniProt | EBI) Last sequence update: 2005-04-12
Last annotation update: 2019-09-18
from provider
RecName: Full=Xin actin-binding repeat-containing protein 1;AltName: Full=Cardiomyopathy-associated protein 1;
Polypeptide 1129 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Xirp1 xin actin-binding repeat containing 1 21 9 5 3
Sequence references in MGI J:52598 Wang DZ, et al., Requirement of a novel gene, Xin, in cardiac morphogenesis. Development. 1999 Mar;126(6):1281-94
J:78855 Sinn HW, et al., Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development. Dev Dyn. 2002 Sep;225(1):1-13
J:129033 Choi S, et al., The intercalated disc protein, mXinalpha, is capable of interacting with beta-catenin and bundling actin filaments. J Biol Chem. 2007 Dec 7;282(49):36024-36
J:132079 Gustafson-Wagner EA, et al., Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. Am J Physiol Heart Circ Physiol. 2007 Nov;293(5):H2680-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory