Sequence Detail

ID/Version

O70324 Q8K3S9 (UniProt | EBI)

Last sequence update: 2006-09-05
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Monocarboxylate transporter 8; Short=MCT 8;AltName: Full=Solute carrier family 16 member 2;AltName: Full=X-linked PEST-containing transporter;

Provider

SWISS-PROT

Sequence

Polypeptide 545 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	50	119	3	13

Sequence references in MGI

J:46800 Debrand E, et al., Cloning and localization of the murine Xpct gene: evidence for complex rearrangements during the evolution of the region around the Xist gene. Genomics. 1998 Mar 15;48(3):296-303
J:77062 Chureau C, et al., Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine. Genome Res. 2002 Jun;12(6):894-908
J:151324 Wirth EK, et al., Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome. J Neurosci. 2009 Jul 29;29(30):9439-49
J:151808 Ceballos A, et al., Importance of monocarboxylate transporter 8 for the blood-brain barrier-dependent availability of 3,5,3'-triiodo-L-thyronine. Endocrinology. 2009 May;150(5):2491-6
J:282621 Roberts LM, et al., Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier. Endocrinology. 2008 Dec;149(12):6251-61
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:326272 Groeneweg S, et al., In Vitro Characterization of Human, Mouse, and Zebrafish MCT8 Orthologues. Thyroid. 2019 Oct;29(10):1499-1510