Sequence Detail

ID/Version

O70293 O70295 O70294 Q6DI67 (UniProt | EBI)

Last sequence update: 1998-08-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=G protein-coupled receptor kinase 6; EC=2.7.11.16;AltName: Full=G protein-coupled receptor kinase GRK6;

Provider

SWISS-PROT

Sequence

Polypeptide 576 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Grk6	G protein-coupled receptor kinase 6	22	101	3	34

Sequence references in MGI

J:57925 Premont RT, et al., The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation. J Biol Chem. 1999 Oct 8;274(41):29381-9
J:76872 Fong AM, et al., Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7478-83
J:83191 Gainetdinov RR, et al., Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice. Neuron. 2003 Apr 24;38(2):291-303
J:86611 Kavelaars A, et al., Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6. J Immunol. 2003 Dec 1;171(11):6128-34
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89