Sequence Detail

ID/Version

O70172 (UniProt | EBI)

Last sequence update: 1998-08-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha {ECO:0000305}; EC=2.7.1.149 {ECO:0000250|UniProtKB:P48426};AltName: Full=1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha;AltName: Full=Diphosphoinositide kinase 2-alpha;AltNa

Provider

SWISS-PROT

Sequence

Polypeptide 405 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	57	103	4	7

Sequence references in MGI

J:46962 Ishihara H, et al., Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/ substitution analysis of members of this novel lipid kinase family. J Biol Chem. 1998 Apr 10;273(15):8741-8
J:132732 Schulze H, et al., Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis. Blood. 2006 May 15;107(10):3868-75
J:262397 Lundquist MR, et al., Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy. Mol Cell. 2018 May 3;70(3):531-544.e9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89