Sequence Detail

ID/Version

O55222 Q78KK2 (UniProt | EBI)

Last sequence update: 2006-10-31
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Scaffold protein ILK {ECO:0000305};AltName: Full=ILK-1 {ECO:0000250|UniProtKB:Q13418};AltName: Full=ILK-2 {ECO:0000250|UniProtKB:Q13418};AltName: Full=Inactive integrin-linked kinase {ECO:0000305};AltName: Full=p59ILK {ECO:0000250|UniProtKB:

Provider

SWISS-PROT

Sequence

Polypeptide 452 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ilk	integrin linked kinase	148	107	3	24

Sequence references in MGI

J:43595 Li F, et al., Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase. Biochim Biophys Acta. 1997 Oct 11;1358(3):215-20
J:116475 Mori K, et al., Oligomerizing potential of a focal adhesion LIM protein Hic-5 organizing a nuclear-cytoplasmic shuttling complex. J Biol Chem. 2006 Aug 4;281(31):22048-61
J:134768 Montanez E, et al., Kindlin-2 controls bidirectional signaling of integrins. Genes Dev. 2008 May 15;22(10):1325-30
J:189982 Matsuda C, et al., Affixin activates Rac1 via betaPIX in C2C12 myoblast. FEBS Lett. 2008 Apr 9;582(8):1189-96
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:352571 Wickstrom SA, et al., Integrin-linked kinase controls microtubule dynamics required for plasma membrane targeting of caveolae. Dev Cell. 2010 Oct 19;19(4):574-88