Sequence Detail

ID/Version

O55188 Q3TZB6 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Dentin matrix acidic phosphoprotein 1 {ECO:0000250|UniProtKB:Q13316}; Short=DMP-1 {ECO:0000303|Ref.2}; Short=Dentin matrix protein 1 {ECO:0000312|MGI:MGI:94910};AltName: Full=AG1 {ECO:0000312|MGI:MGI:94910};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 503 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dmp1	dentin matrix protein 1	19	127	2	18

Sequence references in MGI

J:46696 MacDougall M, et al., Identification of a novel isoform of mouse dentin matrix protein 1: spatial expression in mineralized tissues. J Bone Miner Res. 1998 Mar;13(3):422-31
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:115339 Feng JQ, et al., Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet. 2006 Nov;38(11):1310-5
J:341423 Feng XY, et al., Homeobox protein MSX-1 inhibits expression of bone morphogenetic protein 2, bone morphogenetic protein 4, and lymphoid enhancer-binding factor 1 via Wnt/beta-catenin signaling to prevent differentiation of dental mesenchymal cells during the late bell stage. Eur J Oral Sci. 2018 Feb;126(1):1-12
J:341424 Feng XY, et al., Msx1 regulates proliferation and differentiation of mouse dental mesenchymal cells in culture. Eur J Oral Sci. 2013 Oct;121(5):412-20