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Sequence Detail
O55143 Q9WUT5 Q9R2A9 (UniProt | EBI) Last sequence update: 2000-12-01
Last annotation update: 2018-05-23
from provider
RecName: Full=Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; Short=SERCA2; Short=SR Ca(2+)-ATPase 2; EC=;AltName: Full=Calcium pump 2;AltName: Full=Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch s
Polypeptide 1044 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 76 12 8 59
Sequence references in MGI J:59909 Ver Heyen M, et al., Structure and organization of the mouse Atp2a2 gene encoding the sarco(endo)plasmic reticulum Ca2+-ATPase 2 (SERCA2) isoforms. Mamm Genome. 2000 Feb;11(2):159-63
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:149024 Boyd JH, et al., S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end products. Circ Res. 2008 May 23;102(10):1239-46
J:153342 Stefanovic B, et al., TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis. Mol Cell Biol. 2004 Feb;24(4):1758-68
J:182140 Swift F, et al., Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3997-4001
J:198051 Kim H, et al., Tmem64 modulates calcium signaling during RANKL-mediated osteoclast differentiation. Cell Metab. 2013 Feb 5;17(2):249-60

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory