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Sequence Detail
ID/Version
O54918 A2ALQ6 O54919 O54920 (UniProt | EBI) Last sequence update: 1998-06-01
Last annotation update: 2019-12-11
Sequence
description
from provider
RecName: Full=Bcl-2-like protein 11; Short=Bcl2-L-11;AltName: Full=Bcl2-interacting mediator of cell death;
Provider SWISS-PROT
Sequence
Polypeptide 196 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Bcl2l11 BCL2-like 11 (apoptosis facilitator) 84 4 5 33
Sequence references in MGI J:45671 O'Connor L, et al., Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J. 1998 Jan 15;17(2):384-95
J:85832 Liu X, et al., The structure of a Bcl-xL/Bim fragment complex: implications for Bim function. Immunity. 2003 Sep;19(3):341-52
J:107746 Nitta T, et al., IAN family critically regulates survival and development of T lymphocytes. PLoS Biol. 2006 Apr;4(4):e103
J:167725 Galehdar Z, et al., Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA. J Neurosci. 2010 Dec 15;30(50):16938-48
J:177231 Thompson S, et al., Identification of a novel Bcl-2-interacting mediator of cell death (Bim) E3 ligase, tripartite motif-containing protein 2 (TRIM2), and its role in rapid ischemic tolerance-induced neuroprotection. J Biol Chem. 2011 Jun 3;286(22):19331-9
J:201566 Maurer U, et al., Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol Cell. 2006 Mar 17;21(6):749-60
J:235307 Weber A, et al., The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis. EMBO Rep. 2016 May;17(5):724-38

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory